|
|
NADP+ + bilirubin <=> Biliverdin + NADPH + H+
|
1.3.1.24
biliverdin reductase
|
–
|
| |
BRENDA:
BR40361
KEGG:
R02393
MetaCyc:
BILIVERDIN-REDUCTASE-RXN
SABIO-RK:
2334
|
|
|
|
UDP-glucuronate + bilirubin <=> C12-beta-glucuronosyl-bilirubin-IX_alpha + UDP
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
MetaCyc:
RXN-19359
|
|
|
|
heme + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> Biliverdin + Fe2+ + CO + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.18
heme oxygenase (biliverdin-producing)
|
–
|
| |
MetaCyc:
HEME-OXYGENASE-DECYCLIZING-RXN
|
|
|
|
UDP-glucuronate + C12-beta-glucuronosyl-bilirubin-IX_alpha <=> UDP + bilirubin_diglucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
MetaCyc:
RXN-19361
|
|
|
|
UDP-glucuronate + C8-beta-glucuronosyl-bilirubin-IX_alpha <=> UDP + bilirubin_diglucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
MetaCyc:
RXN-19360
|
|
|
|
UDP-glucuronate + bilirubin <=> C8-beta-glucuronosyl-bilirubin-IX_alpha + UDP
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
MetaCyc:
RXN-19358
|
|
